http://www.ajcn.org/cgi/content/abstract/82/2/350

In this study by Jennie C Brand-Miller et al published in the current edition of the American Journal of Clinical Nutrition,
researchers began with the premise that "IGF (insulin-like growth factors) and IGF-binding protein (IGFBP) responses may be acutely affected by differences in the glycemic index (GI) of foods. "

They then measured the IGF and IGFBP responses after high and low GI meals.

Their conclusion was:
"Acute changes in IGFBP-3 after low-GI and high-GI foods may provide a biologic mechanism linking cell multiplication with greater consumption of high-GI carbohydrates. "

This is a small study, and very limited in what you can conclude from it.

This editorial http://www.ajcn.org/cgi/content/full/82/2/277
in the same issue, explains some of the limitations of the study, but concludes: "The study by Brand-Miller et al suggests that the GI can modulate IGF-I signaling within hours. These findings raise the possibility that, by lowering the dietary GI, we may be able to manipulate the IGF axis to prevent cancer. "

Certainly, more research is needed along these lines.

Very interesting. I think that I just might use this article as inspiration for a presentation that I am going to be making in my cancer biology seminar.

It would be really interesting to dive into the literature and see the actual evidence that sugar/carbs impact cancer.

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Started Atkins on 9/20/03
235-->190; 150 goal